Clinical perspective
Chronic spontaneous urticaria: Understanding the persistent burden of hives
Duration, history, and symptom burden provide a useful starting point when evaluating recurrent hives.

When hives become chronic
Urticaria consists of raised, itchy welts that may be red or skin-colored. Symptoms persisting beyond six weeks warrant consideration of chronic urticaria. In chronic spontaneous urticaria, a clear external trigger often cannot be identified, which can make the condition frustrating for patients.
History guides the evaluation
ACAAI emphasizes the importance of reviewing medical history, exposures, and medications. A record of symptoms over time can support the discussion. Patients may assume that a food allergy explains recurring hives, but foods are not the trigger for most people with chronic spontaneous urticaria.
A continuing care conversation
Antihistamines are a mainstay of management, and ongoing symptoms may require specialist assessment of additional options. The practical goal of follow-up is to understand symptom control and its effect on daily life. Treatment choices should reflect the individual clinical assessment and current guidance rather than a generalized approach to every case of hives.
